NEW DELHI: A new monoclonal antibody treatment has shown promising results for a rare liver disease called primary sclerosing cholangitis (PSC).
The team from the University of California-Davis, US, tested an anti-inflammatory and anti-fibrotic monoclonal antibody known as nebokitug and found it to be safe and potentially effective in patients with PSC.
Published in the American Journal of Gastroenterology, the results offer encouraging news for patients with PSC, for which there are currently no effective treatments short of liver transplantation.
"In the trial, nebokitug demonstrated that it has the potential to change the lives of patients with PSC by reducing fibrosis and inflammation, which should lead to improved outcomes, " said Christopher Bowlus, chief of Gastroenterology and Hepatology at UC Davis Health.